TechTalkXL: Cell & Gene Therapy – 30 June 2026 | NecstGen

TechTalkXL: Cell & Gene Therapy – 30 June 2026 | NecstGen

Which ideas, technologies, and perspectives are currently moving Cell and Gene Therapy forward? On Tuesday, 30 June 2026, NecstGen will host TechTalkXL: Cell & Gene Therapy in Leiden, as part of Dutch Bio Science Week, organised by Leiden Bio Science Park. The event brings together professionals working in or closely following the field of Cell and Gene Therapy for an afternoon of expert presentations, snapshot talks, and peer exchange.

About the Event

Cell and Gene Therapy is advancing across a range of areas, including oncology, rare genetic disorders, and degenerative diseases. Progress in clinical translation, process development, and enabling technologies is shaping what becomes possible and what the next steps look like in practice.

TechTalkXL provides a setting to examine these developments directly, with speakers actively involved in bringing therapies forward. The format is focused and practical: expert presentations followed by shorter snapshot talks and dedicated time to connect with colleagues and peers from across the field.

Programme
15:30 – Arrival & Registration
16:00 – Speaker Session 
17:10 – Snapshot Talks
From 17:30 – Networking

Speakers
There will be an exciting speaker program, including the following experts from the field: 

Snapshot Talks

  • An end-to-end RNA platform – from IVT to formulation – empowering faster, simpler, and scalable therapies production
    • Yuliya Shakalisava, EXIT071
  • Beyond the Cell: Harnessing Exosomes for Diagnostics and Therapeutics
    • Emilie Viey, Quantoom Biosciences
  • Tamar Tak, Leiden University Medical Center
  • TBA, Astraveus

Practical Information

Date: Tuesday, 30 June 2026 Location: Leiden, The Netherlands, Leiden Bio Science Park Participation: Free of charge Registration: Required

TechTalkXL is open to anyone working in or engaged with the field of Cell and Gene Therapy. If this is relevant for you or your team, we invite you to save the date and register via the link below.

Register Now


Events like these are part of NecstGen’s ongoing effort to strengthen collaboration and knowledge exchange across the Cell and Gene Therapy development chain. We look forward to welcoming you in Leiden.




Webinar: ‘Case Study: Development of a Scalable LV Production Platform’

Webinar: ‘Case Study: Development of a Scalable LV Production Platform’

Case Study: Development of a Scalable LV Production Platform

Developing lentiviral vector production processes that scale reliably across different bioreactor platforms requires more than increasing volume. Cell line behaviour, transfection conditions and engineering parameters all interact and can influence vector yield, consistency and process robustness.

What you’ll learn
In this webinar, Lindsay Mulder, Scientist Viral Vector, will present a case study on upstream development of a suspension-based lentiviral vector production platform using HEK293T cells.
The session builds on the concepts introduced in Lodewijk’s previous webinar and provides a step-by-step view of how the process was established and scaled.
Lindsay will discuss a practical case study, where adherent HEK293T cells were adapted to suspension culture and how the resulting cell line was established and characterised for stable GMP vector production.
This webinar will address key questions, including:
  • How does lentiviral vector production differ between adherent and suspension systems?
  • What are the key steps in creating a robust suspension cell bank?
  • How can cell line suitability for GMP production be assessed?
  • What strategies can be used to optimise transfection efficiency?
  • How can scale-up in stirred tank reactors (STRs) be effectively optimised?
  • What considerations are important when designing a scale-up pathway?
  • How can processes be successfully transferred into a GMP environment? 
Register now
If you work in viral vector process development or manufacturing and want to understand how systematic development strategies can support scalable LV production, this session will provide relevant practical insights.
Register now to secure your place and join the discussion.

NecstGen Contributing to the Future of CGT

NecstGen Contributing to the Future of CGT

On 24 April 2026, the Cell & Gene Therapy community gathers at PLNT Leiden for the Future of CGT.

NecstGen is contributing to this conference together with partners across the ecosystem: Health~Holland, JPP – Life Sciences Marketing & BD, Leiden Bio Science Park, OVBSP Leiden, and host PLNT Leiden.

The programme is built for teams actively working in CGT. Expect case studies from real CGT projects with concrete lessons, breakout tracks covering biotech, manufacturing, regulatory, and clinical development, workshops focused on building practical skills, and a partnering setting structured for honest conversations and new collaborations.

Speakers bring direct experience from CGT ventures, clinical development, and the broader ecosystem, covering topics such as financing structures, investor alignment, post-deal continuity, and the path from innovation to patient impact.

If you are building, backing, or scaling in CGT, the content is relevant to your work.

More information on this event & tickets can be found here: https://futureofcgt.com/

Webinar: Scale-up Principles for Viral Vector Production

Webinar: Scale-up Principles for Viral Vector Production

Scale-up Principles for Viral Vector Production

Scaling viral vector production from a few litres to larger stirred bioreactors is rarely a simple volume jump. Oxygen transfer, mixing, shear and power input all start to interact in ways that can affect yield, CQAs and overall process robustness.

What you’ll learn
You will explore the main engineering challenges of scaling stirred bioreactors for viral vectors and compare oxygen transfer via surface aeration and sparging, with a focus on how each approach impacts cells and productivity.

Lodewijk will discuss the factors that drive oxygen mass transfer rates, how to interpret and use kLa, and how power input can be used to balance oxygen transfer, mixing and shear instead of optimising them in isolation. The webinar will address shear from both agitation and aeration, along with practical protection strategies for shear-sensitive products.

Finally, you will see how oxygen transfer characterisation, scale-up criteria, scale-down models and DoE studies come together to de-risk decisions and support smoother tech transfer.

Register now
If you work in process development, MSAT or manufacturing and want a clearer, quantitative basis for your viral vector scale-up strategy, this session is for you.

Register now to secure your place and bring your questions on bioreactor design, oxygen transfer and shear control.

TechTalk XL 2025: Cell & Gene Therapies

TechTalk XL 2025: Cell & Gene Therapies

As part of Dutch Bio Science Week 2025, TechTalkXL brought together the Cell and Gene Therapy community for an afternoon of focused exchange at Mirai House. Organised by NecstGen in collaboration with Leiden Bio Science Park, the event provided a setting to examine both therapeutic development and the practical realities of producing advanced therapies.

Speakers and guests represented a wide range of perspectives from academia, biotech, and early-stage ventures. Discussions covered topics such as gene editing, T-cell engineering, NK cell applications, decentralised manufacturing, data handling, donor safety, and the infrastructure required to support these therapies.

The main programme featured presentations from Frank Staal of LUMC on clinical developments in gene therapy for rare genetic diseases, Ester Weijers of NTrans on a non-viral CRISPR delivery platform, Anna-Maria Georgoudaki of Glycostem on off-the-shelf NK cell therapies, and Gemma Parsons of Galapagos on a decentralised, digitally enabled model for fresh cell therapy manufacturing.

In the snapshot session, shorter talks focused on advances in manufacturing. Topics included modular automation, decentralised production models, advanced sterility testing, closing the process, and data-informed quality systems. Presenters brought insight from KU Leuven, Fraunhofer IPT, Biotactical, WMDA, and NecstGen.

Events like these are part of our broader effort to strengthen collaboration across the Cell and Gene Therapy development chain. The aim is to help bring advanced therapies to patients with greater consistency, confidence, and speed.

We thank all speakers for their contributions and all attendees for making time in a busy week to take part in these conversations.

On September 24, NecstGen will host the next CGT Circle session at Mirai House. Details on the programme and registration will follow shortly. For now, we invite you to save the date.

Photos below capture a few moments from the afternoon. We look forward to welcoming you again.

Webinar Announcement: Improving lentiviral vector yield with 2G UNic technology

Webinar Announcement: Improving lentiviral vector yield with 2G UNic technology

Join NecstGen and ProteoNic for our webinar “Improving lentiviral vector yield with 2G UNic technology”, presented by Maurice van der Heijden (Director of R&D, ProteoNic) and Diederik Lokhorst (Viral Vector Scientist, NecstGen).

Discover more about ProteoNic’s 2G UNic™ technology and how NecstGen has been applying the technology for Lentiviral (LV) production. Learn from our experts while they discuss several aspects of LV production, a major cost driver in both gene therapies and Ex vivo gene therapies, and how both companies are working together to improve it.

Register now to secure your spot and stay tuned for more updates!

Register here

NecstGen Services

Cell Therapy Development & Manufacturing

Viral Vector Development & Manufacturing

Cleanroom Rental

Consultancy

About Us

NecstGen is a non-profit CDMO and Centre of Excellence for Cell and Gene Therapy located in a purpose-built GMP facility in Leiden, The Netherlands. Dedicated to the field of Cell and Gene Therapies, we provide expertise and capacity.

About Us

Partners

History

Facility

Ecosystem