NecstGen launches its first development lab

NecstGen launches its first development lab

NecstGen launches its first development lab

We are happy to announce the launch of NecstGen’s first development laboratory at the Leiden Bio Science Park.

Here, our scientists and analytical experts have started the first process development projects, supporting our clients to bring cell- and viral vector-based therapies to patients. This is another step towards realising NecstGen’s mission to accelerate the development of breakthrough cell and gene therapies.

 

Meanwhile, NecstGen is well underway in the establishment of its GMP facility at Mirai House, which is expected to open its doors in 2022.

Johan Hyllner joins strategic advisory board of NecstGen

Johan Hyllner joins strategic advisory board of NecstGen

Johan Hyllner joins strategic advisory board of NecstGen

NecstGen announces the addition of Johan Hyllner to its strategic advisory board. Johan Hyllner is leading expert in cell therapy and enabling technologies. He is professor of engineering biology at Linköping University, Sweden and head of the Cell Therapy BioPharmaceutical R&D at AstraZeneca. He was responsible for building five startups, including Cellartis and Cellectis, in the cell therapy field into successful international businesses.

“I am excited to join NecstGen’s advisory board. Cell and gene therapies offer great potential to provide something better than existing medicines. It is important to promote this next generation of medicines. NecstGen does this by actively supporting the first steps of their manufacturing. This will ultimately help combat some of the most complex diseases.” Says Prof. Hyllner.

Johan Hyllner obtained his doctorate at the University of Gothenburg. He is devoted to both scientific and industrial aspects of cell therapy, publishing over 60 peer reviewed articles in this field. Since 2012, he is adjunct Professor of engineering biology at the department of Physics, Chemistry and Biology at Linköping University, Sweden. Throughout the last 20 years, Johan was a C-level executive in five startup companies in the cell therapy field and built these into successful international businesses. Among others, as CSO, he has been part of building Cellectis, Cellartis, SQC Lab and Vitrolife into thriving entities. From 2013 he held the position as CSO of the Cell and Gene Therapy Catapult Ltd, London, a high-profile innovation centre established by the British government, where he helped grow the organization from 12 to 170 people. In 2019, he joined AstraZeneca, where he is leading Cell Therapy BioPharmaceuticals R&D. Here, he is responsible for the discovery and development of cell therapy based projects from discovery to clinic across cardiovascular, renal, metabolic, respiratory and immunological diseases. In this role, he oversees the strategic direction of this newly-formed department while building capabilities both internally and through collaborations. Prof. Hyllner brings vast experience in applied research through development to global marketing, manufacturing and commercialization of advanced cell-based products. In addition, he has extensive experience of strategic outlining and execution, external scientific relations, assessment of candidate projects and technical oversight of preclinical programs.

NecstGen contracts Kuijpers for the construction of its Cell and Gene Therapy facility

NecstGen contracts Kuijpers for the construction of its Cell and Gene Therapy facility

NecstGen contracts Kuijpers for the construction of its Cell and Gene Therapy facility

NecstGen announces that the Dutch constructor Kuijpers has obtained the contract for the construction of its Cell- and Gene Therapy facility. Throughout the next year, NecstGen’s facility will be constructed in Mirai House on the largest Life Science and Health hub of The Netherlands, the Leiden Bio Science Park. Kuijpers is specialised in the design and construction of cleanrooms and GMP facilities. As main contractor the company will be responsible for technical installations and construction.

“We are pleased with the collaboration with Kuijpers, and look forward to a successful construction trajectory. This brings us one step closer to realizing our mission – to bring more regenerative therapies, faster to the patient,” comments Paul Bilars, CEO of NecstGen.

NecstGen obtains €2 Million from Province South Holland

NecstGen obtains €2 Million from Province South Holland

NecstGen obtains €2 Million from Province South Holland

Today, Meindert Stolk, deputy Economy and Innovation of the Province South Holland visited NecstGen to hand over a symbolic cheque of € 2 million to Paul Bilars, CEO of NecstGen. Throughout the last years, the province has been closely involved with developments at the Leiden Bio Science Park. This included investments in facilities, networks and collaborations. The € 2 million subsidy has been awarded to support the establishment of NecstGen’s facility at the Leiden Bio Science Park. At this facility, academic and industrial clients can make use of state-of-the-art labs and cleanrooms to develop and produce regenerative therapies.

 

56 million euro from Dutch ‘Groeifonds’ to pilot factory for regenerative therapies

56 million euro from Dutch ‘Groeifonds’ to pilot factory for regenerative therapies

56 million euro from Dutch ‘Groeifonds’ to pilot factory for regenerative therapies

Today, the Dutch cabinet announced the investment of €56 million into the establishment of a “pilot factory” for regenerative therapies. NecstGen and three other facilities will form a chain covering the development and manufacturing of cell therapies, biomaterials, microtissues and macrotissues. The funding is awarded to RegMed XB, a collaboration of research institutes, governments, provinces, health funds, and industry in the Netherlands and Flanders aimed at the development of regenerative therapies and technologies.

Paul Bilars, CEO of NecstGen: “I am very excited about this investment in NecstGen. It will support us in our ambition to advance the development and manufacturing of promising regenerative therapies. We look forward to further strengthen the ecosystem of regenerative medicine in the Netherlands together with our RegMed XB-partners.”

“This pilot factory can focus on an underserved group of therapy developers: academic institutes and small companies.” Sander van Deventer, strategic advisory board member of NecstGen, further adds. “The investment thereby contributes to the continuation of a great pipeline that has been build up in and around the Netherlands”.

NecstGen will be supported by its local partners LUMC, Leiden University and Provincie Zuid-Holland and is currently building its GMP facility at the Leiden Bio Science Park. The company will open its doors in 2022.

NecstGen Services

We offer process development solutions, contract preclinical/ GMP manufacturing and cleanroom rental for Cell and Gene Therapies to clinicians, academic, small, medium, and large commercial organisations worldwide.

Viral Vector Manufacturing & Development

Cleanroom Rental

Cell Therapy Manufacturing & Development

About Us

NecstGen is a non-profit CDMO and Centre of Excellence for Cell and Gene Therapy located in a purpose-built GMP facility in Leiden, The Netherlands. Dedicated to the field of Cell and Gene Therapies, we provide expertise and
capacity to focus on patient solutions.

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