19 February 2025 Leiden, The Netherlands – Modified cells offer an attractive opportunity to cure disease however their inherent complexity requires novel technologies to better understand them. Such technologies could greatly improve Cell Therapy translation and development leading to efficiency and better outcomes for patients.
NecstGen, a non-profit CDMO for Cell & Gene Therapy, and Digi.Bio, a developer of novel lab-on-a-chip technology, have formed a collaboration to improve testing and development for Cell Therapies. This partnership utilises Digi.Bio’s cutting-edge platform to deliver dynamic multiparametric single-cell immunoprofiling, aiming to accelerate the journey from concept to therapeutic.
As the Cell & Gene Therapy industry continues to evolve, the need for more sophisticated development tools and reliable testing methods is critical. Mode of action, efficacy, and safety testing are used to evaluate a therapeutic’s ability to achieve its intended effect and to control risk. Such testing is crucial for the approval and use of Cell and Gene Therapies to treat patients.
Digi.Bio is addressing these challenges with its platform that condenses the typical laboratory processes needed for testing Cell and Gene Therapies into a single microfluidic chip. Leveraging automation, microfluidics, AI and machine learning Digi.Bio’s platform achieves real-time analysis of cell-to-cell behaviour, including their interactions, motility, and therapeutic potential. The partnership with NecstGen provides opportunities for the application of Digi.Bio’s technology to Cell and Gene Therapy development and grants NecstGen access to novel technologies with the potential to speed-up Cell & Gene Therapy development.
“We are proud to collaborate with NecstGen. By bringing together their expertise in Cell & Gene therapy development and our innovative technology we aim to set new benchmarks for the Cell & Gene Therapy industry for efficacy and safety testing and support improving patient outcomes globally.”, adds Federico Muffatto, CEO of Digi.Bio.
“At NecstGen, we are supporting novel technologies that have the potential to accelerate Cell & Gene Therapy development,” said Paul Bilars, CEO of NecstGen. “Partnering with Digi.Bio allows us to leverage their cutting-edge technology to further enhance our testing capabilities, ultimately leading to faster and more reliable development of therapies.”
Watch how Digi.Bio’s technology can bring insights to your therapy development:
About NecstGen
NecstGen is a non-profit CDMO and centre of excellence for Cell and Gene Therapy, located in a purpose-built GMP facility at the Leiden Bio Science Park, the largest bio-cluster in the Netherlands. NecstGen provides critical contract development, manufacturing and rental services to academic and industrial therapy developers to deliver next-generation therapeutics to patients.
About Digi.Bio
Digi.Bio is revolutionizing cell therapy development with its AI-driven, lab-on-a-chip platform. Designed for high-content, real-time analysis, the technology enables dynamic monitoring of immunotherapy performance at single-cell resolution. With BSL-2 laboratories at Leiden Bio Science Park and headquarters in Amsterdam, Digi.Bio provides a digital, single-cell representation of immune therapy responses, offering unprecedented spatial and temporal insights into treatment behavior.
